Guide for Int'l Students
For Prospective Students
Summer Program
Laboratory Research Course
| SUBJECT | Life Sciences and Disease Studies *minimum number of students needed to offer a course: 2 |
|---|---|
| HOURS / CREDIT | 30 hours / 1 credit |
| INSTRUCTOR | Haruhiko MARUYAMA and 10 others |
| AIM OF COURSE | The aim of this course is to introduce participants to recent advances in Life Sciences and Medicine through lectures by distinguished researchers at the University of Miyazaki, working at the cutting edge of each fields. |
| SYLLABUS | 1. Nano-world tour using electron microscopes (1L and 1P) Akira SAWAGUCHI (Ultrastructural Cell Biooogy) This introductory course bring you into a nano-world tour using electron microscopes, observing several biological samples such as insects, human hair, and rat stomach at x1,000 – 50,000 magnification in Bio-Imaging Lab of the Frontier Science Research Center. 2. Introduction of Neuroscience (1L and 1P) Kougo TAKAMIYA (Integrative Physiology) This course is designed for undergraduate-level students, studying biological or medical programs. The course will provide students an understanding of the principles of neurological function, particularly focusing on cellular and molecular mechanisms of neural signaling and plasticity underlying learning and memory. This course also emphasizes the neural anatomy and neurobiological functions for understanding cognition, mental illness and disorders of human behavior. The overall goal is to equip students in molecular neuroscience for interpreting synaptic plasticity, which is the basic mechanism for learning and memory formation It also includes lab tour discussing with researches studying up to date neuroscience in our lab. Our research focus is as follows: Molecular mechanisms of synaptic plasticity underlying memory and learning Synaptic plasticity is a fundamental neuronal function in central nervous system and is observed in many brain regions. It is widely believed that synaptic plasticity is a basic mechanism of learning and memory. Our main research focus is the elucidation of molecular mechanisms of synaptic plasticity. So far we are focusing on the functional roles of AMPA type glutamate receptor in synaptic plasticity, which mediates fast major excitatory neurotransmission in central nervous system and play a primordial function in synaptic plasticity expression. Therefore the modulations of AMPA type glutamate receptor plays critical functional roles in synaptic function and plasticity. Currently we are studying the following projects using molecular biological, biochemical, cell biological and electrophysiological techniques. In addition to heterologous cells, primary culture neurons and originally generated mutant mice have been used to find out answer to our questions. We are also interested in studying several unsolved questions regarding neuronal functions and disease, such as pain, neurodegenerative and psychiatric diseases. Current research projects Analysis of N-glycosylation of AMPA receptor in synaptic transmission and plasticity. Screening of trans-synaptic molecules influencing synaptic functions Studying molecules regulating pain and itch in spinal dorsal horn Analysis of zebra fish model to understand molecular mechanisms of neurodegenerative disease Visualization of synaptic plasticity in vivo using imaging technique 3. Wound healing (2L) Radha Madhyastha, Harishkumar Madhyastha (Applied Physiology) Explain about molecular biology techniques in Physiological field. Then, give a lecture about Wound healing mechanisms and new approach to accelerating the mechanisms. 4. Developing advanced medical diagnosis technology by molecular science (2L and 2P) Yan XU (Chemistry) Imaging of chromosomal DNA has been widely applied to diagnosis of genetic diseases and chromosome architecture analysis. We have developed a novel approach for imaging chromosome DNA with multicolor in place of the traditional dye painting. In this time, we will observe the chromosomal DNA by introducing fluorescent molecules, along with touching the state-of-the-art life science. 5. Developing disease models (1L and 2P) Naoya KENMOCHI (RI research, Frontier Science Research Center) Introductory course for gene knockdown technology using Zebrafish 6. Translational Research of Biologically Active Peptides (3L and 1T) Johji KATO (Biologically Active Peptides, Frontier Science Research Center) 1) Lectures on isolation/identification and clinical application of biologically active peptides; 2) Tour of the laboratories 7. Introduction to Experimental Parasitology (1L and 1T) Haruhiko MARUYAMA(Parasitology) Introductory course for the biology of parasites and research strategy for tackling the riddle of parasites. 8. Analysis of the molecular mechanisms underlying carcinogenesis and leukemogenesis, using cellular, biochemical, molecular, and genetic approaches (2L and 1T) Kazuhiro MORISHITA (Tumor and Cellular Biochemistry) Our research aims to identify genes that are involved in leukemogenesis and carcinogenesis and to resolve the molecular mechanisms underlying these processes, using cellular, biochemical, molecular, and genetic approaches. The goal of our approach is to develop novel strategies for diagnosis and treatment for cancer including leukemia. The major areas of our research include refractory acute myeloid leukemia with chromosome 3q26 (the EVI1 gene) and/or chromosome 7 abnormalities, HTLV-1-associated adult T-cell leukemia/lymphoma, and oral squamous cell carcinoma in collaboration with division of oral and maxillofacial surgery. Please look at our homepage (http://biochem.med.miyazaki-u.ac.jp/english/index.html). 9. Immunology (1L &1T) Katsuaki SATO (Immunology) We will lecture the role of dendritic cells in the immune system, and their potential therapeutic use for immunopathogenic diseases. 10. Molecular and Cellular Pharmacology (1L &1T) Ryu TAKEYA (Pharmacology) This course aims to provide a chance to touch and feel the forefront of molecular and cellular pharmacology through hands-on research experiments. . |
| COMMUNICATIONS | The course tutor’s details are as follows: Office: General Affairs Division, Faculty of Medicine Tel: +81-985-85-9126 email: medsomu@med.miyazaki-u.ac.jp |