Center for International Relations University of Miyazaki

Guide for Int'l Students

For Prospective Students

Summer Program

Laboratory Research Course
SUBJECT Life Sciences and Disease Studies
*minimum number of students needed to offer a course: 2
HOURS / CREDIT 30 hours / 1 credit
INSTRUCTOR Haruhiko MARUYAMA and 11 others
AIM OF COURSE The aim of this course is to introduce participants to recent advances in Life Sciences and Medicine through lectures by distinguished researchers at the University of Miyazaki, working at the cutting edge of each fields.
SYLLABUS 1. Nano-world tour using electron microscopes
Professor Akira SAWAGUCHI (Ultrastructural Cell Biooogy)
 This introductory course bring you into a nano-world tour using electron microscopes, observing several biological samples such as insects, human hair, and rat stomach at x1,000 – 50,000 magnification in Bio-Imaging Lab of the Frontier Science Research Center.

2. Introduction of Neuroscience
Professor Kougo TAKAMIYA (Neuroscience)
 This course is designed for undergraduate-level students, studying biological or medical programs. The course will provide students an understanding of the principles of neurological function, particularly focusing on cellular and molecular mechanisms of neural signaling and plasticity underlying learning and memory. This course also emphasizes the neural anatomy and neurobiological functions for understanding cognition, mental illness and disorders of human behavior.
The overall goal is to equip students in molecular neuroscience for interpreting synaptic plasticity, which is the basic mechanism for learning and memory formation It also includes lab tour discussing with researches studying up to date neuroscience in our lab.

3. Wound healing
Professor Radha Madhyastha, Harishkumar Madhyastha (Applied Physiology)
 Introductory course on physiological events that occur during wound healing, with special focus on fibrinolysis. Participants will be taken through a lecture on wound healing, followed by a practical session (experiment) to identify novel fibrinolytic compounds.

4. Developing advanced medical diagnosis technology by molecular science
Professor Yan XU (Chemistry)
 Imaging of chromosomal DNA has been widely applied to diagnosis of genetic diseases and chromosome architecture analysis. We have developed a novel approach for imaging chromosome DNA with multicolor in place of the traditional dye painting. In this time, we will observe the chromosomal DNA by introducing fluorescent molecules, along with touching the state-of-the-art life science.

5. Developing disease models using zebrafish
Professor Naoya KENMOCHI (RI research, Frontier Science Research Center)
 Students will learn about development and analyses of zebrafish disease models and practice basic techniques such as micro-injection and gene knockdown

6. Translational Research of Biologically Active Peptides
Professor Johji KATO (Biologically Active Peptides, Frontier Science Research Center)
1) Lectures on isolation/identification and clinical application of biologically active peptides;
2) Tour of the laboratories

7. Analysis of the molecular mechanisms underlying carcinogenesis and leukemogenesis, using cellular, biochemical, molecular, and genetic approaches
Professor Kazuhiro MORISHITA (Tumor and Cellular Biochemistry)
  Our research aims to identify genes that are involved in leukemogenesis and carcinogenesis and to resolve the molecular mechanisms underlying these processes, using cellular, biochemical, molecular, and genetic approaches. The goal of our approach is to develop novel strategies for diagnosis and treatment for cancer including leukemia. The major areas of our research include refractory acute myeloid leukemia with chromosome 3q26 (the EVI1 gene) and/or chromosome 7 abnormalities, HTLV-1-associated adult T-cell leukemia/lymphoma, and oral squamous cell carcinoma in collaboration with division of oral and maxillofacial surgery. Please look at our homepage
(http://biochem.med.miyazaki-u.ac.jp/english/index.html).

8. Immunology
Professor Katsuaki SATO (Immunology)
  We will lecture the role of dendritic cells in the immune system, and their potential therapeutic use for immunopathogenic diseases.

9. Introduction to Experimental Parasitology
Professor Haruhiko MARUYAMA(Parasitology)
  Introductory course for the biology of parasites and research strategy for tackling the riddle of parasites.

10. Recent Advances in Molecular Histochemical Techniques
Professor Yoshitaka HISHIKAWA (Histochemistry and Cell Biology)
  The aim of this course is to learn and practice the recent advanced techniques of immunohistochemistry and in situ hybridization in molecular histochemistry.

11.Cellular stress response
Professor Yasunari TAKAMI (Biochemistry and Molecular Biology)
  In eukaryotic cells, organelles are constantly exposed to the various stresses. Cells possess the stress responses to maintain their functions. However, if these stress conditions are prolonged, they are implicated in variety of diseases including the neurodegenerative disease, metabolic disease, inflammatory disease, diabetes and cancer through the stress signaling from the organelles. We are focusing on the mechanisms of intracellular organelle stress signaling and organelle quality control systems. In recent years, especially ER stress and mitochondrial stress are main themes in our laboratory. Our final goal is to shed light on the treatment of organelle stress-related disease.

12. Epidemiological Tour of Department of Public Health
Professor Yoshiki KURODA (Department of Public Health) and 2 staff members
  We will show around our laboratory, and give a lecture about our below researchers 1) Epidemiological study concerning to SFTS 2) Molecular epidemiology: Relationship between some gene polymorphisms and carcinogenesis, life related diseases
COMMUNICATIONS
Tutor:Aya Iuchi
Office: Faculty of Medicine Student Affairs Department
Tel: +81-985-85-9714
email: aya_iuchi@med.miyazaki-u.ac.jp